Ivermectin, an ignored Covid miracle drug

Invermectin is an anti-viral, anti-inflammatory drug that is cheap, effective against COVID-19 and already approved by the U.S. Food and Drug Administration.

It has been approved for use in 20 countries, including India, Brazil and Mexico.

Yet the World Health Organization and U.S. Food and Drug Administration do not recommend it.  Many American physicians refuse to prescribe it, including some cases in which patients are dying.

News about it has been suppressed.  Even announcements by health ministries of Brazil and Slovakia have been canceled by social media, as has a YouTube video of testimony of Dr. Pierre Kory, a leading Ivermectin expert, before a congressional committee.

I learned about Ivermectin’s through a link on the Naked Capitalism web log to an article by a journalist named Michael Capuzzo.

I’m not a physician or medical expert, but the evidence presented by Capuzzo in his article, by Dr. Kory in his testimony, and by a team of physicians in a peer-reviewed article is so strong I can’t see how it can be refuted.

Why the opposition to use of this drug?   Nick Corbishley, writing for Naked Capitalism, suggested three possible reasons.

# As a generic, ivermectin is cheap and widely available, which means there would be a lot less money to be made by Big Pharma if it became the go-to medicine against covid.

# Other pharmaceutical companies are developing their own novel treatments for Covid-19 which would have to compete directly with ivermectin. They include ivermectin’s original manufacturer, Merck, which has an antiviral compound, molnupiravir, in Phase 3 clinical trials for COVID-19.  That might explain the company’s recent statement claiming that there is “no scientific basis whatsoever for a potential therapeutic effect of ivermectin against COVID-19.”  The company also flagged up “a concerning lack of safety data in the majority of studies.”  Despite its obvious conflict of interest, Merck’s objections were recently cited by WHO in a statement aimed at browbeating India’s government into withdrawing its approval of ivermectin.

# If approved as a covid-19 treatment, ivermectin could even threaten the emergency use authorization granted to covid-19 vaccines. One of the basic conditions for the emergency use authorization granted to the vaccines currently being used against covid is that there are no alternative treatments available for the disease. As such, if ivermectin or some other promising medicine such as fluvoxamine were approved as an effective early treatment for Covid-19, the vaccines could be stripped of authorization.

Source: naked capitalism

I can think of an additional reason: the tribal nature of politics these days.  President Donald Trump criticized the WHO and CDC and speculated about unconventional therapies for COVID-19.  So anybody who is skeptical about WHO and CDC recommendations supposedly is an ignoramus who doesn’t “believe the science.”

LINKS

‘I Don’t Know of a Bigger Story in the World’ Right Now Than Ivermectin by Nick Corbishley for Naked Capitalism.

The Drug That Cracked Covid by Michael Capuzzo for Mountain Home.  It’s a real commentary on things that this article was published in a obscure regional magazine rather than the New York Times or The Atlantic.

Testimony of Pierre Kory, M.D., on Dec. 8, 2020, before the Homeland Security Committee on early treatment of COVID-19.

Review of the Emerging Evidence Demonstrating the Efficacy of Ivermectin in the Prophylaxis and Treatment of COVID-19 by Drs. Paul Marik, Pierre Kory, Joseph Varon, Gianfranco Umberto Meduri, Jose Iglesias and five others for the Front Line Covid-19 Critical Care Alliance.  These guys are heroes.

Finnish firm earns US patent for Covid drug containing ivermectin and hydroxychoroquinine on Yle News (Finland). [Added 5/26/2021]

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3 Responses to “Ivermectin, an ignored Covid miracle drug”

  1. spinchainthrough Says:

    Ivermectin has been known for some time as a ‘miracle’ drug from Australia (where the protocol was devised) to USA and championed by Dr. P.Kory. In Dec 2020 there is a video of him pleading with the American Senate hearing to allowing this drug to be used. He and the drug were vilified. Finally after jumping through many hurdles by the FDA and WHO it was granted Emergency Use Authorization for ‘off label’ use. The same thing happened with Hydroxychloroquine (HCQ) and Dr. Zelenko. As a matter of fact the Nobel Prize committee has nominated Dr. Zelenko for a Nobel Prize due to his outstanding COVID outpatient treatment protocol involving HCQ. Of course we have not heard one syllable about that.

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  2. Fred (Au Natural) Says:

    Ivermectin does not prevent COVID-19. Nor is it a cure. It is no reason to slow the development or administration of vaccines. There isn’t a competition here.

    If a doctor wants to use it off-label, they are free to do so.

    It is commonly available and easily tolerated. The CDC has studies indicating results ranging from neutral to somewhat good. They further state that the studies are methodologically suspect. Not exactly the signature of a miracle drug. CDC isn’t going to give a glowing recommendation on something with inconclusive results.

    https://www.covid19treatmentguidelines.nih.gov/therapies/antiviral-therapy/ivermectin/

    I looked at the studies and drew the conclusion that it might reduce hospital stay time a day or two for many people. That is significant but not a miracle. The studies had many flaws. Most common was a small sample size. Groups of less than a hundred are not all that useful. Also not double-blind, and not controlled for other treatments. Also, not many subjects were severely ill and people with preexisting complications weren’t often included.

    https://www.covid19treatmentguidelines.nih.gov/tables/table-2c/

    So we have a drug that has the potential of some benefit but the extent of that benefit isn’t clear and hasn’t been backed up by any large-scale study. The most convincing argument that it isn’t a miracle drug is that Brazil and other countries haven’t waved it as a magic wand to make their epidemics go away. They still want their vaccines.

    This is part of the human condition. People get desperate and start looking for straws to grasp. Something comes along that might offer a small benefit. (Or maybe something in use proves to have a small hazard.) Other people decide that this is a horse they can ride so they blow it way out of proportion to what the facts on the ground justify. The people who desperately want that quick fix (or automatically default to conspiracy theory) flock to them in droves.

    Real science is boring and gurus are flashy and full of emotion and quick solutions.

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    • philebersole Says:

      If the NIH report covered all the evidence there is, it would be convincing. It lists a few clinical trials in which the results were inconclusive.

      But the FLCCC report [https://covid19criticalcare.com/wp-content/uploads/2020/11/FLCCC-Ivermectin-in-the-prophylaxis-and-treatment-of-COVID-19.pdf] provides a much larger number of clinical trials in which the results are positive.

      Admittedly, none of these individual trials was in itself conclusive because of small sample sizes and other limitations. But when you have a large number of trials, all leading to the same conclusion, you have a good argument for that conclusion.

      The NIH report also ignores reports of successes of invermectin in the field. Again, if you had just one example of ivermectin being used and the Covid-19 infection and death rate falling, this would not necessarily prove anything. But when you have many examples, all pointing to the same conclusion, you have a good argument for that conclusion.

      It’s possible that invermectin is not what it’s cracked up to be. But since it is proven safe and cheap, why the campaign to discourage its use? If there is a need for a more rigorous clinical trial, one that is beyond the resources of individual physicians, why not conduct such a trial?

      I’m sorry to say that I no longer trust the NIH, the CDC or the WHO to give me unbiased information.

      Liked by 1 person

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